Product | Impamorelin 10mg

Impamorelin 10mg

Ipamorelin 10mg — Selective GHS-R1a ghrelin receptor agonist GHRP research peptide (CAS 170851-70-4). Minimal cortisol/prolactin effects. 99% purity, USA domestic. Same-day shipping. Free shipping over $200.

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Ipamorelin 10mg — Selective GHRP Research Peptide

Ipamorelin 10mg is a research-grade selective growth hormone releasing peptide (GHRP) (CAS 170851-70-4, C38H49N9O5, 711.86 g/mol) and potent ghrelin receptor (GHS-R1a) agonist. As a pentapeptide (Aib-His-D-2-Nal-D-Phe-Lys-NH2), ipamorelin is distinguished from earlier GHRPs (GHRP-2, GHRP-6) by its high GHS-R1a selectivity and minimal stimulation of cortisol, prolactin, and ACTH — making it the most studied selective GH secretagogue for clean GH axis pathway research. Frequently combined with CJC-1295 No DAC for synergistic pituitary GH release studies.

What Is Ipamorelin?

  • Selective GHS-R1a agonism — potent ghrelin receptor activation without ACTH/cortisol crosstalk
  • Synergistic GH release — powerful combination with GHRH analogs (CJC-1295) for additive GH pulse studies
  • GH/IGF-1 axis activation — dose-dependent GH and IGF-1 increase in pre-clinical models
  • Selectivity research — comparison of GHS-R1a selectivity vs. GHRP-2, GHRP-6, hexarelin
  • Cardioprotective signaling — GHS-R1a-mediated cardiac ghrelin signaling studies
  • Body composition research — GH-mediated lipolysis and lean tissue studies

Why Ipamorelin vs. Other GHRPs?

GHRPGHS-R1a PotencyCortisol/ACTH EffectSelectivity
IpamorelinHighMinimalHighest
GHRP-2HighModerateModerate
GHRP-6HighModerate-HighLow
HexarelinVery HighHighLow

Common Research Applications

Ipamorelin 10mg (CAS 170851-70-4) is used in professional pre-clinical research for:

  • Selective GHS-R1a receptor activation and downstream GH signaling assays
  • Combination GHRH/GHRP synergy studies (ipamorelin + CJC-1295 No DAC)
  • GH/IGF-1 pulse modeling with minimal HPA axis interference
  • GHRP selectivity and receptor subtype pharmacology research
  • Cardiac ghrelin receptor signaling and cardioprotection models
  • Body composition, lipolysis, and lean mass GH axis studies

Why Researchers Buy Ipamorelin from Combat Research

When searching for ipamorelin 10mg for sale or a trusted source to buy ipamorelin research peptide, researchers choose Combat Research:

  • 99% purity — verified by third-party analytical testing
  • USA domestic stock — no international delays
  • Same-day shipping on all in-stock orders
  • Free shipping on orders over $200
  • 5% crypto discount available on every order

Chemical & Physical Properties

PropertyValue
CAS Number170851-70-4
Also Known AsIpamorelin, NNC 26-0161, Impamorelin
Molecular FormulaC38H49N9O5
Molecular Weight711.86 g/mol
SequenceAib-His-D-2-Nal-D-Phe-Lys-NH2 (pentapeptide)
Receptor TargetGHS-R1a (Ghrelin Receptor)
FormLyophilized Powder
Vial Size10mg
Purity≥99%
StorageRefrigerated, protected from light and moisture

Handling & Reconstitution

Ipamorelin 10mg is supplied as a lyophilized powder. Reconstitute with bacteriostatic water or sterile saline under aseptic conditions. Store at 2–8°C. Minimize freeze-thaw cycles.

Research Use Only

Ipamorelin (CAS 170851-70-4) is sold exclusively for pre-clinical and in vitro laboratory research. Not for human or animal consumption. All use must comply with applicable regulations.

Frequently Asked Questions — Impamorelin 10mg

What is Ipamorelin?

Ipamorelin (CAS 170851-70-4, C38H49N9O5, 711.86 g/mol) is a synthetic pentapeptide GHRP and selective ghrelin receptor (GHS-R1a) agonist. Unlike GHRP-2 and GHRP-6, ipamorelin produces potent GH release with minimal stimulation of cortisol, prolactin, or ACTH, making it the most selective GHRP for clean GH axis pathway research.

What makes Ipamorelin different from GHRP-2 and GHRP-6?

Ipamorelin is the most GHS-R1a-selective GHRP available. GHRP-2 and GHRP-6 both stimulate cortisol and prolactin release alongside GH. Ipamorelin achieves equivalent or superior GH release with minimal HPA axis crosstalk, providing cleaner GH secretagogue signaling for research applications.

What is the CAS number for Ipamorelin?

CAS 170851-70-4. Also known as NNC 26-0161. Molecular formula C38H49N9O5, MW 711.86 g/mol. Pentapeptide sequence: Aib-His-D-2-Nal-D-Phe-Lys-NH2. PubChem CID: 9831659.

Why is Ipamorelin often combined with CJC-1295 No DAC?

Ipamorelin (GHS-R1a agonist) and CJC-1295 No DAC (GHRH-R agonist) activate two complementary pituitary GH secretion pathways simultaneously. Combined, they produce synergistic GH release significantly greater than either alone – a widely studied combination in pre-clinical GH axis research.

What research applications does Ipamorelin have?

Ipamorelin is studied for selective GHS-R1a receptor pharmacology, GH/IGF-1 pulse modeling without HPA crosstalk, GHRH/GHRP combination synergy, cardiac ghrelin receptor signaling, GHRP selectivity comparisons, and body composition GH axis research.

How do you reconstitute Ipamorelin?

Reconstitute with bacteriostatic water or sterile saline under aseptic conditions. Gently swirl until dissolved. Store at 2-8 degrees Celsius. Minimize freeze-thaw cycles.

Where can I buy Ipamorelin 10mg research peptide?

Ipamorelin 10mg is available from Combat Research with 99% purity, USA domestic stock, same-day shipping, and free shipping on orders over .

Scientific References & Further Reading

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