Product | CJC-1295 No DAC

CJC-1295 No DAC

CJC-1295 No DAC (Mod GRF 1-29) — Short-acting GHRH analog research peptide (CAS 863288-34-0). Pulsatile GH release. 99% purity, USA domestic. Same-day shipping. Free shipping over $200.

$39.99

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CJC-1295 No DAC (Mod GRF 1-29) — Short-Acting GHRH Analog Research Peptide

CJC-1295 No DAC — also known as Modified GRF (1-29) or Mod GRF 1-29 — is a research-grade short-acting GHRH analog (CAS 863288-34-0) comprising the first 29 amino acids of human GHRH with four strategic amino acid substitutions (Ala2→D-Ala, Gln8→Ala, Ser15→Ala, Leu27→Ala) that resist enzymatic degradation and extend plasma half-life to approximately 30 minutes — producing sharper, more physiological pulsatile GH release patterns than long-acting analogs like CJC-1295 DAC. This makes it the preferred compound for studies requiring GH pulse modeling, endogenous rhythm studies, or combination protocols with GHRPs.

What Is CJC-1295 No DAC (Mod GRF 1-29)?

  • Pulsatile GHRH receptor agonism — stimulates pituitary GH release in physiological burst pattern
  • ~30 min plasma half-life — 4-substitution stability without albumin-binding DAC modification
  • GH/IGF-1 axis activation — dose-dependent GH and downstream IGF-1 increase in rodent models
  • GHRP synergy — potent synergistic GH release when combined with ipamorelin or GHRP-2/6
  • Physiological GH pulsatility modeling — replicates natural GH pulse patterns vs. sustained release of DAC variants
  • Enzymatic stability research — dipeptidyl peptidase IV (DPP-IV) resistance vs. native GHRH

CJC-1295 No DAC vs. CJC-1295 DAC

PropertyCJC-1295 No DAC (Mod GRF 1-29)CJC-1295 DAC
Half-Life~30 minutes~6-8 days
GH PatternPulsatile (physiological)Sustained elevation
Albumin BindingNoYes (via DAC technology)
Best ForGH pulse modeling, GHRP combination researchLong-duration sustained GH studies

Common Research Applications

CJC-1295 No DAC 10mg is used in pre-clinical research settings for:

  • Pulsatile GH secretion pattern modeling and pituitary GHRH-R activation
  • GH/IGF-1 axis stimulation in physiological pulse studies
  • Combination GHRH/GHRP synergy research (e.g., CJC-1295 No DAC + ipamorelin)
  • Comparative pharmacokinetics vs. native GHRH and long-acting GHRH analogs
  • DPP-IV enzyme resistance and peptide stability studies
  • Body composition and metabolic pathway GH axis research

Why Researchers Buy CJC-1295 No DAC from Combat Research

When searching for CJC-1295 No DAC for sale or a trusted source to buy Modified GRF 1-29 research peptide, researchers choose Combat Research:

  • 99% purity — verified by third-party analytical testing
  • USA domestic stock — no international delays
  • Same-day shipping on all in-stock orders
  • Free shipping on orders over $200
  • 5% crypto discount available on every order

Chemical & Physical Properties

PropertyValue
CAS Number863288-34-0
Also Known AsCJC-1295 (no DAC), Mod GRF (1-29), Modified GRF 1-29, GHRH (1-29) analog
SubstitutionsD-Ala2, Ala8, Ala15, Ala27 (vs. native GHRH)
Half-Life~30 minutes
FormLyophilized Powder
Vial Size10mg
Purity≥99%
StorageRefrigerated, protected from light and moisture

Handling & Reconstitution

CJC-1295 No DAC is supplied as a lyophilized powder. Reconstitute with bacteriostatic water or sterile saline under aseptic conditions. Store at 2–8°C refrigerated. Minimize freeze-thaw cycles.

Research Use Only

CJC-1295 No DAC (CAS 863288-34-0) is sold exclusively for pre-clinical and in vitro laboratory research. Not for human or animal consumption. All use must comply with applicable regulations.

Frequently Asked Questions — CJC-1295 No DAC

What is CJC-1295 No DAC (Mod GRF 1-29)?

CJC-1295 No DAC (CAS 863288-34-0), also called Modified GRF (1-29), is a short-acting GHRH analog comprising the first 29 amino acids of GHRH with four amino acid substitutions (D-Ala2, Ala8, Ala15, Ala27) for DPP-IV resistance. It has a ~30-minute plasma half-life and produces pulsatile GH release. Used exclusively in pre-clinical research.

What is the difference between CJC-1295 No DAC and CJC-1295 DAC?

CJC-1295 No DAC (Mod GRF 1-29) has a ~30-minute half-life and produces pulsatile, physiological GH bursts. CJC-1295 DAC uses albumin-binding technology for a 6-8 day half-life producing sustained GH elevation. Choice depends on whether study design requires pulsatile (No DAC) or sustained (DAC) GH patterns.

What is the CAS number for CJC-1295 No DAC?

CAS 863288-34-0. Also known as Modified GRF (1-29), Mod GRF 1-29, and CJC-1295 without DAC. A 29-amino acid stabilized GHRH analog.

Why combine CJC-1295 No DAC with Ipamorelin?

CJC-1295 No DAC activates the GHRH receptor to stimulate pituitary GH release. Ipamorelin activates the ghrelin receptor (GHS-R1a) via a complementary mechanism. Combined, they produce synergistic GH release significantly greater than either compound alone, making this a widely studied combination in pre-clinical GH secretagogue research.

What research applications does CJC-1295 No DAC have?

CJC-1295 No DAC is studied for pulsatile GHRH receptor activation, GH/IGF-1 axis pulse modeling, GHRH/GHRP synergy protocols, DPP-IV enzyme resistance studies, comparative pharmacokinetics vs. native GHRH and CJC-1295 DAC, and body composition GH axis research.

How do you reconstitute CJC-1295 No DAC?

Reconstitute with bacteriostatic water or sterile saline under aseptic conditions. Gently swirl until dissolved. Store at 2-8 degrees Celsius. Minimize freeze-thaw cycles.

Where can I buy CJC-1295 No DAC research peptide?

CJC-1295 No DAC (Mod GRF 1-29) is available from Combat Research with 99% purity, USA domestic stock, same-day shipping, and free shipping on orders over .

Scientific References & Further Reading

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