Product | GLP-2 10MG

GLP-2 10MG

GLP-2 10mg — Glucagon-Like Peptide-2 intestinotrophic research peptide (CAS 106612-94-6). GLP-2R agonist. 99% purity, USA domestic. Same-day shipping. Free shipping over $200.

$64.99

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GLP-2 10mg — Glucagon-Like Peptide-2 Research Peptide

GLP-2 10mg is a research-grade synthetic Glucagon-Like Peptide-2 (CAS 106612-94-6), a 33-amino acid intestinotrophic hormone co-secreted with GLP-1 from intestinal L-cells in response to nutrient ingestion. GLP-2 activates the GLP-2 receptor (GLP-2R), expressed primarily in intestinal epithelium, enteric neurons, and subepithelial myofibroblasts, driving gut mucosal growth, barrier integrity, and nutrient absorption. The FDA-approved GLP-2 analog teduglutide (Gattex®) validates the clinical significance of GLP-2R signaling. The 10mg vial suits pilot studies, receptor binding assays, and protocol validation for GLP-2 pathway research.

What Is GLP-2?

Intestinal epithelial proliferation — GLP-2R-mediated crypt cell proliferation and villus growth in gut models
Gut barrier integrity — tight junction protein upregulation and intestinal permeability reduction
Nutrient absorption enhancement — increased transport protein expression and blood flow to gut mucosa
Anti-apoptotic signaling — inhibition of enterocyte apoptosis and mucosal preservation models
Enteric nervous system — GLP-2R signaling in enteric neurons and subepithelial myofibroblasts
Short bowel syndrome models — intestinal adaptation and mucosal rehabilitation studies

Common Research Applications

GLP-2 10mg (CAS 106612-94-6) is used in professional pre-clinical research for:

GLP-2 receptor activation and downstream cAMP/PKA signaling assays
Intestinal mucosal growth and crypt-villus architecture studies
Gut barrier function and tight junction protein modulation research
Nutrient malabsorption and short bowel syndrome pre-clinical models
Inflammatory bowel disease gut repair pathway investigations
Comparative GLP-2 analog pharmacology vs. teduglutide
Enteric nervous system and subepithelial myofibroblast signaling research

Why Researchers Buy GLP-2 from Combat Research

When searching for GLP-2 10mg for sale or a trusted source to buy GLP-2 research peptide online, researchers choose Combat Research:

✔ 99% purity — verified by third-party analytical testing
✔ USA domestic stock — no international delays or customs risk
✔ Same-day shipping on all in-stock orders
✔ 2–3 day average delivery across the continental US
✔ Free shipping on orders over $200
✔ 5% crypto discount available on every order

Chemical & Physical Properties

Property	Value
CAS Number	106612-94-6
Also Known As	GLP-2, Glucagon-Like Peptide-2, Proglucagon (126-158)
Amino Acids	33
Receptor Target	GLP-2R (Glucagon-Like Peptide-2 Receptor)
FDA Analog	Teduglutide (Gattex®) for short bowel syndrome
Form	Lyophilized Powder
Vial Size	10mg
Purity	≥99%
Storage	Refrigerated, protected from light and moisture

Handling & Reconstitution

GLP-2 10mg is supplied as a lyophilized powder. Reconstitute with bacteriostatic water or sterile saline under aseptic conditions. Store refrigerated at 2–8°C. Minimize freeze-thaw cycles.

Research Use Only

GLP-2 (CAS 106612-94-6) is sold exclusively for pre-clinical and in vitro laboratory research. Not for human or animal consumption. All use must comply with applicable regulations.

Frequently Asked Questions — GLP-2 10MG

What is GLP-2 (Glucagon-Like Peptide-2)?

GLP-2 (CAS 106612-94-6) is a 33-amino acid intestinotrophic hormone co-secreted with GLP-1 from intestinal L-cells. It activates the GLP-2 receptor (GLP-2R) to promote gut mucosal growth, barrier integrity, nutrient absorption, and enterocyte survival. The FDA-approved analog teduglutide (Gattex) validates its clinical significance.

What is GLP-2 used for in research?

GLP-2 is studied for intestinal epithelial proliferation and crypt-villus architecture, gut barrier tight junction modulation, short bowel syndrome and intestinal adaptation models, inflammatory bowel disease repair research, nutrient malabsorption studies, and GLP-2R receptor pharmacology.

What is the CAS number for GLP-2?

CAS 106612-94-6. GLP-2 is a 33-amino acid peptide also known as Proglucagon(126-158). The FDA-approved GLP-2 analog teduglutide (Gattex) confirms the pathway’s therapeutic significance. PubChem CID: 56841553.

How is GLP-2 different from GLP-1?

GLP-1 activates GLP-1R to stimulate insulin secretion and suppress appetite – a metabolic and anti-obesity target. GLP-2 activates GLP-2R to promote intestinal growth and gut barrier integrity – an intestinotrophic and mucosal repair target. They are co-secreted from the same L-cells but have distinct receptor targets and research applications.

Is there an FDA-approved GLP-2 analog?

Yes. Teduglutide (Gattex) is an FDA-approved GLP-2 analog for short bowel syndrome (SBS). The research peptide GLP-2 (CAS 106612-94-6) is the native sequence used in pre-clinical studies investigating GLP-2R pathways and intestinal biology.

How do you reconstitute GLP-2 research peptide?

Reconstitute GLP-2 with bacteriostatic water or sterile saline under aseptic conditions. Gently swirl until dissolved. Store at 2-8 degrees Celsius refrigerated. Minimize freeze-thaw cycles to preserve peptide integrity.

What is GLP-2 10mg best suited for?

GLP-2 10mg is ideal for pilot GLP-2R binding studies, intestinal epithelial proliferation assays, initial dose-response development, and protocol validation before committing to higher-volume research programs.