GLP-3 15 mg

Retatrutide 15mg (GLP-3) — Triple Agonist Research Peptide

Retatrutide 15mg — also marketed as GLP-3 — delivers a mid-range research quantity of the GLP-1/GIP/glucagon triple receptor agonist peptide (LY-3437943, CAS 2381089-83-2), engineered for extended pre-clinical studies and multi-run experimental protocols. Retatrutide concurrently activates GLP-1, GIP, and glucagon receptors, providing researchers a powerful tool for investigating coordinated metabolic receptor signaling. The 15mg vial is best suited for laboratories running multiple experimental arms or requiring greater compound volume without committing to bulk quantities.

What Is Retatrutide (GLP-3)?

Retatrutide (GLP-3, LY-3437943) is a precision-engineered triple agonist peptide designed to simultaneously bind and activate three metabolic receptor types:

• GLP-1 receptors — key targets in incretin signaling, insulin secretion pathway studies, and glucoregulatory research
• GIP receptors — involved in glucose-dependent insulinotropic polypeptide research and beta-cell function modeling
• Glucagon receptors — studied for roles in glycogen mobilization, energy balance, and counter-regulatory hormone research

Unlike single or dual receptor agonists, retatrutide enables comprehensive investigation of all three receptor pathways in a single experimental design, reducing variability and compound costs in multi-target signaling studies.

Common Research Applications

Retatrutide 15mg (GLP-3, LY-3437943) is used across professional research settings for:

• Multi-run GLP-1, GIP, and glucagon receptor activation studies
• Extended metabolic signaling pathway analysis requiring consistent compound supply
• Dose-response curve development across receptor subtypes
• Peptide receptor interaction and binding kinetics research
• Comparative studies between retatrutide and single or dual agonist compounds
• Hormonal crosstalk and synergistic signaling investigations
• Assay development and optimization requiring repeated compound access

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Chemical & Physical Properties

Handling & Reconstitution

Retatrutide 15mg (GLP-3) is supplied as a lyophilized (freeze-dried) powder to maintain structural integrity and potency during storage and shipping. Before experimental use, reconstitute with an appropriate research-grade diluent such as bacteriostatic water or sterile saline under aseptic conditions. Store reconstituted peptide refrigerated and use within recommended timeframes for optimal research outcomes.

Research Use Only

Retatrutide (GLP-3, LY-3437943, CAS 2381089-83-2) is intended exclusively for in vitro and pre-clinical scientific research. This compound is not approved for human or animal therapeutic use and must not be administered to humans or animals. All use must be conducted in compliance with applicable local, state, and federal regulations governing research compounds.

Frequently Asked Questions — Retatrutide 15mg (GLP-3)

Scientific References & Further Reading

• PubChem — Retatrutide / LY-3437943 (CAS 2381089-83-2)
• ChEMBL — CHEMBL5095485