MOTS-C 40MG

MOTS-C 40mg — Mitochondrial-Derived Research Peptide (Best Value)

MOTS-C 40mg is the highest-volume offering of Combat Research’s mitochondrial-derived peptide (MDP) (CAS 1627580-76-4), designed for high-throughput metabolic research programs, long-duration experimental protocols, and multi-arm studies requiring the best per-milligram value on MOTS-C. As a 16-amino acid retrograde signaling peptide encoded in the mitochondrial 12S rRNA region, MOTS-C is studied for AMPK pathway activation, insulin sensitivity, exercise mimetic signaling, and mitochondria-to-nucleus crosstalk — making it one of the most important compounds in modern mitochondrial biology research.

What Is MOTS-C?

• Mitochondria-to-nucleus retrograde signaling — novel MDP class coordinating metabolic responses across cellular compartments
• AMPK activation via folate cycle inhibition — AICAR accumulation drives AMPK-mediated metabolic reprogramming
• Insulin sensitivity — enhances glucose uptake and insulin receptor pathway signaling in skeletal muscle
• Exercise mimetic — replicates exercise-induced metabolic adaptations and AMPK signaling in pre-clinical models
• Longevity and healthspan — circulating MOTS-C declines with age; studied for age-associated metabolic decline
• Stress resilience and mitohormesis — cellular adaptive stress response and mitochondrial quality control research

Common Research Applications

MOTS-C 40mg (CAS 1627580-76-4) supports the most demanding research programs:

• High-throughput AMPK pathway and metabolic signaling assay pipelines
• Long-duration insulin sensitivity and glucose homeostasis longitudinal studies
• Multi-arm exercise mimetic and metabolic adaptation comparative studies
• Comprehensive dose-response, receptor saturation, and kinetics profiling
• Aging and longevity pathway multi-cohort experimental designs
• Mitochondrial peptide comparative studies (MOTS-C vs. humanin vs. SHLPs)
• Inter-lab method transfer and reproducibility studies requiring high compound volume

Why Researchers Buy MOTS-C 40mg from Combat Research

For researchers seeking the best source to buy MOTS-C 40mg or purchase MOTS-C research peptide in bulk, Combat Research delivers unmatched value:

• ✔ 99% purity — every batch independently verified
• ✔ Best per-mg value — 40mg maximizes compound output per research dollar
• ✔ USA domestic stock — no international delays
• ✔ Same-day shipping on all in-stock orders
• ✔ Free shipping on orders over $200
• ✔ 5% crypto discount available on every order

Chemical & Physical Properties

Handling & Reconstitution

MOTS-C 40mg is supplied as a lyophilized powder. Reconstitute with bacteriostatic water or sterile saline under aseptic conditions. Store at 2–8°C. Limit freeze-thaw cycles to preserve peptide integrity across extended research timelines.

Research Use Only

MOTS-C (CAS 1627580-76-4) is sold exclusively for pre-clinical and in vitro laboratory research. Not for human or animal consumption. All use must comply with applicable regulations.

Frequently Asked Questions — MOTS-C 40MG

Scientific References & Further Reading

• PubChem — MOTS-c (CAS 1627580-76-4)