Product | GLP-1 10mg

GLP-1 10mg

Semaglutide 10mg (GLP-1) — Best value GLP-1 receptor agonist research peptide (CAS 910463-68-2). Same compound as Ozempic/Wegovy. 99% purity, USA domestic. Same-day shipping. Free shipping over $200.

$64.99

53 in stock (can be backordered)

CERTIFICATE OF ANALYSIS

CERTIFICATE OF ANALYSIS

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Semaglutide 10mg (GLP-1) — GLP-1 Receptor Agonist Research Peptide

Semaglutide 10mg — sold under the GLP-1 category — is a research-grade synthetic GLP-1 receptor agonist (CAS 910463-68-2, C187H291N45O59, 4113.58 g/mol) with 94% sequence homology to native human Glucagon-Like Peptide-1. The 10mg vial is designed for established research programs, extended multi-run experimental protocols, and high-throughput GLP-1R studies requiring uninterrupted compound availability — delivering the best per-milligram value for semaglutide research. Semaglutide’s C18 fatty diacid albumin-binding modification — the same mechanism in Ozempic® and Wegovy® — provides a ~7-day plasma half-life model for sustained GLP-1R signaling studies.

What Is Semaglutide (GLP-1 Receptor Agonist)?

Semaglutide activates the GLP-1 receptor (GLP-1R), a class B GPCR with broad tissue expression critical for metabolic research:

  • Pancreatic beta cells — glucose-dependent insulin secretion and beta-cell survival pathway studies
  • Hypothalamus & brainstem — central appetite suppression, satiety signaling, and energy homeostasis research
  • Cardiovascular tissue — GLP-1R-mediated cardioprotection, heart rate modulation, and vascular signaling
  • Liver — hepatic glucose output, de novo lipogenesis inhibition, and steatosis models
  • Kidney — renal nephroprotective and anti-inflammatory GLP-1R pathway investigations
  • CNS — dopaminergic reward pathway modulation and neuroprotection research

Common Research Applications

Semaglutide 10mg (GLP-1, CAS 910463-68-2) supports a wide range of high-output research programs:

  • Extended GLP-1R binding, activation, and downstream cAMP/PKA signaling studies
  • Long-duration insulin secretion and beta-cell function protocols
  • Comprehensive dose-response and receptor saturation curve development
  • Multi-cohort obesity and metabolic syndrome pre-clinical models
  • Cardiovascular and renal GLP-1R signaling research programs
  • Comparative GLP-1R agonist potency studies vs. tirzepatide and retatrutide (GLP-3)
  • Albumin-binding pharmacokinetics and fatty acid side chain modification research

Why Researchers Buy Semaglutide from Combat Research

For researchers searching for semaglutide 10mg for sale or the best source to buy semaglutide research peptide in bulk, Combat Research delivers unmatched quality, value, and speed:

  • 99% purity — every batch independently verified for purity and identity
  • Best per-mg value — 10mg vial maximizes compound output per research dollar
  • USA domestic stock — no international shipping delays or import complications
  • Same-day shipping on all in-stock orders
  • 2–3 day average delivery across the continental United States
  • Free shipping on orders over $200
  • 5% crypto discount available on every order
  • Batch-to-batch consistency critical for multi-run reproducibility

Chemical & Physical Properties

PropertyValue
CAS Number910463-68-2
Also Known AsSemaglutide, GLP-1 agonist, Ozempic (brand), Wegovy (brand), Rybelsus (brand)
Molecular FormulaC187H291N45O59
Molecular Weight4113.58 g/mol
Receptor TargetGLP-1R (Glucagon-Like Peptide-1 Receptor)
Plasma Half-Life~7 days (albumin-bound via C18 fatty diacid)
Sequence Homology94% to native human GLP-1
FormLyophilized Powder
Vial Size10mg
Purity≥99%
StorageRefrigerated, protected from light and moisture

Semaglutide vs. Tirzepatide vs. Retatrutide (GLP-3) — Research Comparison

CompoundReceptor TargetsAgonist TypeHalf-Life
Semaglutide (GLP-1)GLP-1RSingle agonist~7 days
TirzepatideGLP-1R + GIPRDual agonist~5 days
Retatrutide (GLP-3)GLP-1R + GIPR + Glucagon RTriple agonist~6 days

Handling & Reconstitution

Semaglutide 10mg is supplied as a lyophilized (freeze-dried) powder. Reconstitute with bacteriostatic water or sterile saline under strict aseptic conditions. Store reconstituted solution refrigerated at 2–8°C. Limit freeze-thaw cycles to preserve C18 fatty diacid side chain integrity across extended research timelines.

Research Use Only

Semaglutide (CAS 910463-68-2) is sold exclusively for pre-clinical and in vitro laboratory research. This product is not for human or animal consumption outside of FDA-approved clinical indications. All research use must comply with applicable local, state, and federal regulations governing research compounds.

Frequently Asked Questions — GLP-1 10mg

What is Semaglutide (GLP-1)?

Semaglutide (CAS 910463-68-2, C187H291N45O59, 4113.58 g/mol) is a synthetic GLP-1 receptor agonist with 94% sequence homology to native human GLP-1. Modified with a C18 fatty diacid chain for albumin binding, it has a ~7-day plasma half-life and is studied for GLP-1R activation, insulin secretion signaling, and metabolic pathway research.

Is Semaglutide the same as Ozempic or Wegovy?

Semaglutide is the active compound in Ozempic (diabetes management), Wegovy (weight management), and Rybelsus (oral formulation) – all FDA-approved brand-name drugs. The research peptide semaglutide (CAS 910463-68-2) is the same molecule sold strictly for pre-clinical laboratory research use only.

What receptors does Semaglutide target?

Semaglutide is a selective GLP-1 receptor (GLP-1R) agonist. GLP-1R is expressed in pancreatic beta cells, hypothalamus, brainstem, liver, heart, and kidney, enabling multi-tissue research into insulin secretion, appetite regulation, cardiovascular signaling, and metabolic homeostasis.

How is Semaglutide different from tirzepatide or retatrutide (GLP-3)?

Semaglutide is a single GLP-1R agonist. Tirzepatide is a dual GLP-1/GIP agonist. Retatrutide (GLP-3) is a triple GLP-1/GIP/glucagon agonist. Semaglutide provides the most GLP-1R-selective research profile for isolated incretin pathway studies.

What is the CAS number for Semaglutide?

CAS 910463-68-2. Molecular formula C187H291N45O59, molecular weight 4113.58 g/mol. PubChem CID 56843331. ChEMBL ID CHEMBL3301622.

How do you reconstitute Semaglutide research peptide?

Reconstitute with bacteriostatic water or sterile saline under aseptic conditions. Gently swirl until dissolved. Store refrigerated at 2-8 degrees Celsius. Minimize freeze-thaw cycles to preserve the C18 fatty diacid side chain integrity.

What is Semaglutide 10mg best suited for in research?

Semaglutide 10mg supports extended research programs requiring consistent compound supply: multi-run dose-response studies, long-duration GLP-1R signaling protocols, comparative agonist studies, and high-throughput metabolic pathway assays where the 5mg quantity would require frequent reordering.

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