Sermorelin 10mg — Native-sequence GHRH(1-29) research peptide (CAS 86168-78-7). Pulsatile GH release, pituitary GHRH-R agonist. 99% purity, USA domestic. Same-day shipping. Free shipping over $200.
$32.99
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Sermorelin 10mg is a research-grade synthetic analog of growth hormone-releasing hormone (GHRH) comprising the first 29 amino acids of endogenous human GHRH (CAS 86168-78-7, 3357.88 g/mol) — the biologically active N-terminal fragment responsible for pituitary GH stimulation. Unlike CJC-1295 variants, sermorelin preserves the native GHRH(1-29) amino acid sequence without additional substitutions, providing a natural-sequence research model for GHRH receptor activation and pulsatile GH release physiology. Sermorelin is the closest research analog to endogenous GHRH available for pre-clinical GH axis studies.
| Compound | Sequence | Half-Life | Modifications |
|---|---|---|---|
| Sermorelin | Native GHRH(1-29) | ~10-20 min | None |
| CJC-1295 No DAC | Modified GRF(1-29) | ~30 min | 4 substitutions |
| Tesamorelin | GHRH(1-44) analog | ~25-30 min | trans-3-hexenoic acid |
| CJC-1295 DAC | Modified GRF(1-29)+DAC | ~6-8 days | 4 subs + albumin binding |
Sermorelin 10mg (CAS 86168-78-7) is used in pre-clinical research settings for:
When searching for sermorelin 10mg for sale or a trusted source to buy sermorelin research peptide, researchers choose Combat Research:
| Property | Value |
|---|---|
| CAS Number | 86168-78-7 |
| Also Known As | Sermorelin acetate, GHRH (1-29) NH2, Geref (historical brand) |
| Molecular Weight | 3357.88 g/mol |
| Amino Acids | 29 (native GHRH N-terminal fragment) |
| Half-Life | ~10-20 minutes |
| Form | Lyophilized Powder |
| Vial Size | 10mg |
| Purity | ≥99% |
| Storage | Refrigerated, protected from light and moisture |
Sermorelin 10mg is supplied as a lyophilized powder. Reconstitute with bacteriostatic water or sterile saline under aseptic conditions. Store at 2–8°C. Minimize freeze-thaw cycles.
Sermorelin (CAS 86168-78-7) is sold exclusively for pre-clinical and in vitro laboratory research. Not for human or animal consumption. All use must comply with applicable regulations.
Sermorelin (CAS 86168-78-7, 3357.88 g/mol) is a synthetic peptide comprising the first 29 amino acids of human growth hormone-releasing hormone (GHRH). It activates pituitary GHRH receptors to stimulate pulsatile GH release. Unlike CJC-1295 variants, sermorelin preserves the native GHRH(1-29) sequence without additional amino acid substitutions.
Sermorelin uses the native GHRH(1-29) sequence with ~10-20 min half-life. CJC-1295 No DAC has four amino acid substitutions extending half-life to ~30 minutes. CJC-1295 DAC adds albumin-binding for 6-8 day half-life. Sermorelin provides the closest native-sequence GHRH pharmacology model.
CAS 86168-78-7 (acetate salt). Also known as GHRH(1-29)NH2 and sermorelin acetate. MW 3357.88 g/mol. 29-amino acid native GHRH N-terminal fragment. PubChem CID: 16133672.
Sermorelin is studied for native GHRH receptor activation, pulsatile GH secretion pattern modeling, GH/IGF-1 axis stimulation, comparative GHRH pharmacology vs. modified analogs, GHRH/somatostatin feedback axis research, and GH deficiency pre-clinical models.
Yes. Sermorelin (GHRH receptor agonist) combined with GHRPs like ipamorelin (GHS-R1a agonist) produces synergistic GH release via complementary pituitary signaling pathways – a widely studied combination in pre-clinical GH secretagogue research.
Reconstitute with bacteriostatic water or sterile saline under aseptic conditions. Gently swirl until dissolved. Store at 2-8 degrees Celsius. Minimize freeze-thaw cycles.
Sermorelin 10mg is available from Combat Research with 99% purity, USA domestic stock, same-day shipping, and free shipping on orders over .
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